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KARYA TULIS ILMIAH STUDI PENGGUNAAN OBAT ANTIHIPERTENSI (BISOPROLOL) PADA PASIEN GAGAL JANTUNG RAWAT JALAN DI RUMAH SAKIT “X” PERIODE OKTOBER-DESEMBER 2020
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ABSTRAK
Hipertensi suatu keadaan dimana tekanan darah seseorang 140 mmHg atau lebih (tekanan sistolik) dan 90 mmHg atau lebih (tekanan diastolik). Penyempitan dan penyumbatan pembuluh darah yang disebabkan hipertensi dapat meningkatkan risiko timbulnya gagal jantung. Bisoprolol lebih aman dan efektif untuk pengendalian denyut jantung.. Metode penelitian ini Deskriptif Observasional dengan teknik purposive sampling. Jumlah sampel 40 pasien yang memenuhi kriteria inklusi dengan parameter: karakteristik pasien (jenis kelamin, usia), dosis terapi, aturan pakai, lama pemberian, jenis terapi (terapi tunggal/kombinasi, terapi obat antihipertensi tunggal/kombinasi), data klinis (tekanan darah sistolik dan diastolik). Hasil penelitian karakteristik jenis kelamin terbanyak laki-laki 65% (n=26) dan usia terbanyak kategori lansia akhir 56-65 tahun 35% (n=14). Dosis pemberian obat bisoprolol tablet terbanyak pada dosis terapi 5 mg 52,5% (n=21). Aturan pakai terbanyak yaitu sehari sekali 90% (n=36) dengan lama permberian terapi keseluruhan diberikan selama 30 hari 100% (n=100). Jenis terapi terbanyak menggunakan terapi bisoprolol kombinasi 97,5% (n=39) dengan kombinasi terbanyak yaitu Bisoprolol, Furosemide dan Spironolactone sebanyak 12,5% (n=5).Data klinis (tekanan darah sistolik dan diastolik) hasil terbanyak perbaikan tekanan darah sistolik turun 67,5% (n=27) dan terbanyak tekanan darah diastolik tetap 57,5% (n=23). Berdasarkan penjelasan diatas disarankan penelitian selanjutnya dapat menggunakan antihipertensi golongan lain sebagai pembanding keefektivitasannya dan untuk data klinik ( tekanan darah sistolik dan diasistolik) selanjutnya dapat dilakukan kurang dari 1 bulan sehingga pengawasan perbaikan tekanan darah pasien dapat diamati dengan lebih signifikan.
ABSTRACT
Hypertension is a condition in which a person's blood pressure is 140 mmHg or more (systolic pressure) and 90 mmHg or more (diastolic pressure). Narrowing and blockage of blood vessels caused by hypertension can increase the risk of heart failure. Bisoprolol is safer and more effective for controlling heart rate. This research method is descriptive observational with purposive sampling technique. The number of samples was 40 patients who met the inclusion criteria with parameters: patient characteristics (gender, age), therapeutic dose, rules of use, duration of administration, type of therapy (single/combination therapy, single/combination antihypertensive drug therapy), clinical data (blood pressure) systolic and diastolic). The results of the research on gender characteristics were mostly male, 65% (n=26) and the most age group in the late elderly category, 56-65 years, 35% (n=14). The highest dose of bisoprolol tablet was administered at a therapeutic dose of 5 mg 52.5% (n=21). The most commonly used rule is once a day 90% (n=36) with the overall duration of therapy given for 30 days 100% (n=100). The most type of therapy used combination bisoprolol therapy 97.5% (n=39) with the most combinations being Bisoprolol, Furosemide and Spironolactone as much as 12.5% (n=5). Clinical data (systolic and diastolic blood pressure) showed the most improvement in blood pressure. systolic blood pressure decreased 67.5% (n=27) and the highest diastolic blood pressure remained 57.5% (n=23). Based on the explanation above, it is suggested that further research can use other classes of antihypertensive as a comparison of its effectiveness and for further clinical data (systolic and diastolic blood pressure) it can be carried out in less than 1 month so that monitoring of improvement in patient blood pressure can be observed more significantly.
Detail Information
| Item Type |
KARYA TULIS ILMIAH
|
|---|---|
| Penulis |
Tantrie Yunita - Personal Name
|
| Student ID | |
| Dosen Pembimbing |
Apt. Andri Priyoherianto, S.Farm., M.Si - - Dosen Pembimbing 1
|
| Penguji |
Apt. Merry Patrilinila Chresna, S.Farm., M.Kes - - Ketua Penguji
Apt. M. Rizky Arif, M.Farm - - Penguji 1 Apt. Andri Priyoherianto, S.Farm., M.Si - - Penguji 2 |
| Kode Prodi PDDIKTI | |
| Edition |
Published
|
| Departement | |
| Contributor | |
| Language |
Indonesia
|
| Publisher | Akademi Farmasi Mitra Sehat Mandiri Sidoarjo : Krian., 2021 |
| Edition |
Published
|
| Subject(s) | |
| No Panggil |
615.14 TAN s
|
| Copyright | |
| Doi |