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KARYA TULIS ILMIAH UJI MUTU FISIK METOCLOPRAMIDE HCL TABLET KUNYAH DENGAN JENIS VARIASI PENGIKAT (GELATIN,PVP K-30 DAN AMYLUM MAYDIS) DENGAN METODE GRANULASI BASAH SECARA SPEKTROFOTOMETRI UV-Vis
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Metoklopramide HCI is used to easing nausea and vomiting. We can find easily in tablet, syrup, and injection. Oral use is the most preferred by patients because easily to use it. The chewable tablet is the new product as alternative for children and people medication having hard to swallow medicine.This research intends for formulating the availability the chewable tablet of metoclopramide HCI using types of variation of the binder ( gelatin, PVP K-30 and amylum maydis) with wet granulation method we look forward it can make better physical quality test involve organoleptic, uniformity of weights, uniformity of size, hardness of tablets, fragility of tablets, disintegration time, determination of content. The result of physical test is analyzed statistically by One Way ANOVA to determine the effect of the type of binder variation on the characteristics of chewable tablets.The results of the research is made from three formulas using different binders but theconcentration is same (gelatine 2%, PVP K-302%, amylum maydis2%). Based on the experiment results we know that gelatin as a binder make tablet which has relatively large hardness, small fragility, and durable. Amilum maydis as binder which makes tablet that has small hardness, large fragility, and not durable. Pvp k-30 as a binder which makes tablet that has small hardness, relatively large fragility, and not durable.
Detail Information
| Item Type |
KARYA TULIS ILMIAH
|
|---|---|
| Penulis |
Suyanti Andhika - Personal Name
|
| Student ID | |
| Dosen Pembimbing |
Apt. Deny Budi Legowo, S.Farm., M.Farm - - Dosen Pembimbing 1
|
| Penguji |
Apt. Valiandri Puspadina, S.Farm., M.Farm - - Ketua Penguji
Dr. Iswandi, S.Si, M.Farm., Apt - - Penguji 1 Apt. Deny Budi Legowo, S.Farm., M.Farm - - Penguji 2 |
| Kode Prodi PDDIKTI | |
| Edition |
Published
|
| Departement | |
| Contributor | |
| Language |
Indonesia
|
| Publisher | Akademi Farmasi Mitra Sehat Mandiri Sidoarjo : Krian., 2020 |
| Edition |
Published
|
| Subject(s) | |
| No Panggil |
615.10724 SUY u
|
| Copyright | |
| Doi |