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Kategori: Jurnal - Dibaca: 192304 kali

Date: Monday, April 29, 2019
Statistics: 15 words Plagiarized / 130 Total words
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The antituberculosis Activity of Benzylidene Acetone Analogues Against Sensitive and Resistant strain of Mycobacterium Tuberculosis Abstract: Curcumin is a compound have many pharmacological activities, but has bad stability compound and bioavailability. Therefore modification should be conducted in curcumin structure. Curcumin analogues modification such as Benzylidene acetone or Gamavutton (GVT) series.

The purposed this study is to determined the anti mycobacterium tuberculosis activity of GVT inhibit Mycobacterium tuberculosis on sensitive strain(H37Rv). Furthermore, to determining the resistant strain (HE and SR). The anti-tuberculosis assay used agar dilution method with serial concentration are 0,125; 0,250; 0,500 and 1,000 mg/mL; and the observation’s time is every week until eighths week. Based on the research, GVT (0,125 mg/mL) have activity to inhibiting Resistant and Sensitive strain of Mycobacterium tuberculosis.

Keywords: tuberculosis, Curcumin analogues,Mycobacterium tuberculosis, GVT



7% - http://www.iosrjournals.org/iosr-jdms/papers/Vol16-issue12/Version-6/E1612062126.pdf

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